Among the sidequests you can start and complete in the Minato ward is the To Cure a Curse sidequest. Here’s how to complete it.
How to Complete the To Cure a Curse Sidequest in Shin Megami Tensei V
The To Cure a Curse sidequest can be started by speaking with the Andras located near the Onarimon Leyline Fount in the Minato ward. The exact location can be found on the map above.
This Andras needs five Bicorn Horns to create a special medicine for healing, so all you need to do to complete the quest is bring them to him. You can get Bicorn Horns by defeating Bicorns, which can be found in the location marked on the map below.
Bicorns are weak to Electric attacks, so use Zio skills to take them down easily. Once you have obtained the five horns, go back to the Andras to complete the quest and receive a Fallen Talisman and 700 EXP points as reward. Additionally, you can get two Spirit Gems every time you bring Andras five Bicorn Horns from now on. This item lets you drain MP from the enemies, so they can be quite useful when in a bind.